Skin Care Ingredient Spotlight: Allantoin

Ingredient Investigation into Allantoin - Cosmetic Composition

Since it’s freezing cold in this country I’ve been paying more attention to the ingredients in my lotions and moisturizers. I’m not sure if this ingredient is gaining popularity or if it’s a golden moisturizing ingredient but I started noticing allantoin pop up everywhere lately!


Allantoin, also known as, 5-ureidohydantoin or glyoxyldiureide, is commonly extracted from the comfrey plant or can be made synthetically in a lab. It is produced from uric acid, which is a normal component of urine, and is a derivative of urea – which you may know is a super moisturizing ingredient. Allantoin is a keratolytic ingredient (more on this soon) that is naturally present in many biological systems and has a variety of skin applications. It is found in the urine of all mammals except for humans and some gorillas – but is surprisingly found in the urine of pregnant women.


As I mentioned earlier allantoin is a moisturizing keratolytic ingredient. Keratolytic means it has the ability to shed extra skin found in the top layer of the skin – the epidermis. By removing excess skin from the epidermis this triggers skin cell formation, which creates softer skin and allows the skin’s moisture retention to increase in the extracellular matrix. Allantoin is a great ingredient to use for acne scars, burns, eczema, and general scaring. Many companies include anti-aging claims for allantoin, however, this is no clinical researching showing its effectiveness.

Tl;dr Allantoin is a keratolytic ingredient that removes excess skin from the epidermis, which induces cell proliferation so it smoothes and moisturizes the skin.

Allantoin Skin Care Ingredient - Cosmetic Composition


Traditionally used in wound healing creams, allantoin is now a very common cosmetic ingredient included in formulas for skin care, lipstick, sunscreen, shampoo, dental products and plenty more. Its historical applications have shown allantoin’s safety for use on humans. Allantoin is gentle enough for sensitive skin, and can even be beneficial when used in products like sunscreens as it can be less irritating for the consumer.

So there you have it! My quick investigation into the moisturizing skincare ingredient allantoin. Go check out some of your cosmetic and personal care products I’m sure you’ll be able to find it in a few formulas.

Any questions or comments? I’d love to hear below! 

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